■ 学会名
MEDINFO2025

■ 発表日
2025/08/11

■ 筆頭演者
Saki Takeshita¹
1) Department of Public Health, Health Management and Policy, Nara Medical University, Nara, Japan

■ 共同演者
Yuichi NISHIOKA¹,², Emiri MORITA¹, Tomoya MYOJIN¹,³, Tatsuya NODA¹, Takashi SUGIYAMA⁴, Tomoaki IMAMURA¹
1) Department of Public Health, Health Management and Policy, Nara Medical University, Nara, Japan
2) Department of Diabetes and Endocrinology, Nara Medical University, Nara, Japan
3) Department of Community Health and Preventive Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan
4) Department of Obstetrics and Gynecology, Ehime University Graduate School of Medicine, Ehime, Japan

■ 発表形態
Poster

■ 要旨
We emulated a target trial of oral contraceptive pills (OCPs) and thrombosis using administrative claims database. OCP users and non-users were matched 1:1 using exact-matching algorithm. 14,554 women were analyzed, and 30 thrombotic events were observed during follow-up. Women using OCPs with 50 μg of ethinyl estradiol (EE) had a 4.3-fold (95% confidence interval: 2.0-6.7) higher thrombotic risk compared to non-users, and women using pills with EE < 50 μg had a 1.0-fold (0.3-1.7) risk, with small differences according to progestin type. Analysis of real-world data can generate novel evidence for public health research questions.