Publication List

Many research outcomes are continuously published every year by pharmaceutical companies and academia using the DeSC database. We provide feedback to insurers on research outcomes and the utilization of anonymized personal information for activities that contribute to effective and efficient healthcare services within local governments.

2026.09.28

Pharmacological management of knee and hip osteoarthritis stratified by oral nonsteroidal anti-inflammatory drugs safety status

DOI：https://doi.org/10.1007/s00774-026-01762-8
2026.09.24

Association between current heated tobacco product use and incident hypertension: A nationwide real-world cohort study

DOI：https://doi.org/10.1038/s41440-026-02817-z
2026.08.31

Real-world trends in radiotherapy modalities for esophageal cancer: analysis of a nationwide claims database in Japan

DOI：https://doi.org/10.1007/s10388-026-01248-6
2026.08.30

Antidepressant initiation after sublingual immunotherapy in Japanese cedar pollinosis: a real-world propensity score-matched cohort study

DOI：https://doi.org/10.1080/03007995.2026.2722388
2026.08.29

Risk of Heart Failure Hospitalization Associated With Hypoxia‐Inducible Factor Prolyl Hydroxylase Inhibitors Versus Erythropoiesis‐Stimulating Agents: A Nationwide Claims‐Based Cohort Study

DOI：https://doi.org/10.1002/pds.70453
2026.08.21

Risk of bone fracture following saccharated ferric oxide in Japan

DOI：https://doi.org/10.1016/j.bone.2026.118056
2026.08.19

Association between non-communicable diseases and work productivity and health-related quality of life among Japanese workers: a cross-sectional study using a claims database and survey data

DOI：https://doi.org/10.1136/bmjopen-2025-115665
2026.08.18

Considering Deintensification and Deprescribing with Higher HbA1c Targets in Vulnerable Older Adults with Type 2 Diabetes: A Retrospective Database Study

DOI：https://doi.org/10.1007/s13300-026-01905-0
2026.08.08

Treatment status of iron medications for anemia in patients visiting gynecological or obstetric facilities: analyses using Japanese claims data

DOI：https://doi.org/10.1186/s12905-026-04769-5
2026.08.07

Real-world osteoporosis management before and after sustaining fragility fractures in Japanese older adults aged ≥ 75 years: Japanese bone-fracture osteoporosis in late-stage population database (J-BOLD) study

DOI：https://doi.org/10.1016/j.jos.2026.07.012
2026.07.27

Clinical Reality and Outcomes of Home Semi-Solid Enteral Nutrition Guidance and Management Using a Medical Claims Database in Japan: A Retrospective Cohort Study

DOI：https://doi.org/10.3390/nu18152442
2026.07.22

Osteoarthritis risk associated with denosumab in adults with osteoporosis: a target trial emulation

DOI：https://doi.org/10.1093/jbmr/zjag113
2026.07.17

Prescription patterns of sacubitril/valsartan among patients with hypertension in Japan

DOI：https://doi.org/10.3389/fcvm.2026.1738988
2026.07.17

Impact of Hydrogel Spacer on Radiation Proctitis After Prostate Cancer Radiation Therapy: A Large-Scale Claims Database Analysis

DOI：https://doi.org/10.1016/j.adro.2026.102145
2026.07.03

Effectiveness of Metformin in Preventing Colorectal Cancer Among Japanese Patients With Type 2 Diabetes: A Target Trial Emulation

DOI：https://doi.org/10.1002/pds.70429
2026.07.02

Methotrexate and folic acid supplementation in rheumatoid arthritis: A Japanese claims database and 538,985 patients from April 2015 to November 2020

DOI：https://www.doi.org/10.5414/CP205023
2026.06.22

Do the treatment selection factors emphasized in clinical guidelines-Chronic kidney disease, cardiovascular disease, and heart failure-contribute to the risk of urinary tract infections during the administration of sodium-glucose cotransporter-2 inhibitors?

DOI：https://doi.org/10.1111/jdi.70362
2026.06.13

Trends in anti-osteoporosis pharmacotherapy and pharmacological initiation for secondary fracture prevention in Japan, 2017–2023

DOI：https://doi.org/10.1016/j.bone.2026.117979
2026.06.12

Dysmenorrhea patients’ experience with work productivity impact and treatment in Japan

DOI：https://doi.org/10.1186/s12905-026-04588-8
2026.06.09

Effectiveness of Amenamevir Vs. Valacyclovir in Preventing Herpes Zoster-Related Hospitalization and Complications: A Target Trial Emulation Using a Large Japanese Claims Database

DOI：https://doi.org/10.1111/1346-8138.70349
2026.06.07

The risk of type 1 diabetes mellitus after COVID-19 and influenza infection: A nationwide cohort and self-controlled case series study

DOI：https://doi.org/10.1016/j.diabres.2026.113366
2026.05.29

Durvalumab After Chemoradiotherapy for Locally Advanced NSCLC: A Real-World Analysis Using a Nationwide Claims Database in Japan

DOI：https://doi.org/10.1016/j.cllc.2026.05.010
2026.05.28

Radiotherapy utilization in the last 30 days before death among patients with malignant neoplasms in Japan: a claims database study

DOI：https://doi.org/10.1007/s10147-026-03076-1
2026.05.26

Anemia visits and clinical patterns after identification of low hemoglobin at health checkups among women of reproductive age in Japan: a real-world claims and health checkup data study (AWARD study)

DOI：https://doi.org/10.1080/03007995.2026.2676157
2026.05.22

Real-World Implementation of Treatment Intensification After Methotrexate in Rheumatoid Arthritis in the Context of Treat-to-Target Recommendations: Insights From Japan’s Claims Data

DOI：https://doi.org/10.1093/mr/roag046
2026.05.21

Impact of National Policies Promoting Appropriate Antibiotic Use on Outpatient Prescriptions and Hospitalizations for Bacterial Complications of Acute Respiratory Infections in Japan: An Interrupted Time-Series Analysis

DOI：https://doi.org/10.1093/ofid/ofag312
2026.05.19

Impacts of cost-sharing rate increment on the expenditure of outpatient care among older adults: quasi-experimental study of cost-sharing reform in Japan

DOI：https://doi.org/10.1186/s12913-026-14387-4
2026.05.19

Myelodysplastic syndromes and risk of kidney function decline: findings from a nationwide Japanese cohort study

DOI：https://doi.org/10.1093/ckj/sfag020
2026.05.19

Effects of individual sodium‑glucose cotransporter‑2 inhibitors on all‑cause mortality in patients with diabetic kidney disease

DOI：https://doi.org/10.1007/s10157-026-02865-2
2026.05.19

Comparative Cardiovascular Effectiveness of GLP-1RAs versus DPP-4is in Dialysis Patients with Type 2 Diabetes: A Target Trial Emulation

DOI：https://doi.org/10.1016/j.diabet.2026.101760
2026.05.19

Drug-specific risks of acute kidney injury associated with triple whammy therapy: a nationwide self-controlled case series study in Japan

DOI：https://doi.org/10.1186/s40780-026-00560-8
2026.05.19

Development of a time-dependent prediction model for the risk of Pneumocystis jirovecii pneumonia in patients with ANCA-associated vasculitis

DOI：https://doi.org/10.1093/rheumatology/keag168
2026.05.19

Discontinuation of Heart Failure Pharmacotherapy in Older Adults with Frailty

DOI：https://doi.org/10.1161/JAHA.125.047638
2026.05.19

Long-Term Outcomes and Therapeutic Strategies for Newly Diagnosed Crohn’s Disease in the Biologic Era: A Nationwide Claims-Based Study from Japan

DOI：https://doi.org/10.31662/jmaj.2025-0438
2026.05.15

Treatment Persistence with Combination Eye Drops for Glaucoma: A Longitudinal Analysis Using Japanese Medical Claims Data

DOI：https://doi.org/10.1007/s40123-026-01384-3
2026.05.14

Prescribing medications for attention-deficit/hyperactivity disorder in children: a retrospective analysis of a Japanese health insurance claims database

DOI：https://www.doi.org/10.1186/s12888-026-08147-1
2026.05.07

Oral bisphosphonates and risk of incident osteoarthritis in individuals with osteoporosis: a target trial emulation

DOI：https://doi.org/10.1136/rmdopen-2026-006832
2026.05.04

Association between pharmacy medication reconciliation proportions and polypharmacy statuses in older adults

DOI：https://doi.org/10.1093/ijpp/riag042
2026.04.21

Early adoption of lecanemab in Japan (December 2023-December 2024): Pretreatment diagnostic timelines from the DeSC claims database

DOI：https://doi.org/10.1177/13872877261443634
2026.04.21

Timing of Remdesivir Initiation and Clinical Outcomes in Hospitalized Patients with COVID-19 Who Are at High Risk of Disease Progression in Japan: A Health Insurance Claims Database Study

DOI：https://doi.org/10.3390/v18040479
2026.04.20

Impact of a national reimbursement add-on policy on refracture risk and secondary fracture prevention after hip fracture in Japan: a population-based interrupted time series analysis

DOI：https://doi.org/10.1007/s00198-026-08023-4
2026.04.17

Romosozumab versus teriparatide for risk of dementia in individuals with osteoporosis: a target trial emulation study

DOI：https://doi.org/10.1007/s00198-026-08026-1
2026.03.13

The impact of slope-adjusted visit-to-visit body mass index variability on early dementia risk prediction

DOI：https://doi.org/10.1038/s41366-026-02052-z
2026.03.09

Comparison of SGLT2 inhibitors for new-onset proteinuria risk in patients with type 2 diabetes and preserved kidney function

DOI：https://doi.org/10.1111/dom.70625
2026.02.11

Appropriate definition of childbirth using Japanese administrative database: A cross-sectional cohort validation study

DOI：https://doi.org/10.1186/s12884-026-08797-9
2026.02.09

Blood Pressure‐Lowering Effect of SGLT2 Inhibitors in Patients Without Antihypertensive Treatment: A Real‐World Data Analysis

DOI：https://doi.org/10.1111/jch.70214
2026.02.01

Nationwide trends in physician consultation and surgical management for pelvic organ prolapse in Japan, 2014 to 2024: a health insurance claims database analysis

DOI：https://doi.org/10.1016/j.xagr.2026.100613
2026.01.26

Long-term outcomes associated with istradefylline versus catechol-O-methyltransferase inhibitors in patients with Parkinson’s disease: a nationwide real-world cohort study

DOI：https://doi.org/10.1016/j.parkreldis.2026.108211
2026.01.23

SGLT2 inhibitors and mortality in older adults with diabetic kidney disease: A target trial emulation study

DOI：https://doi.org/10.1111/dom.70502
2026.01.20

Risk of acute pancreatitis with DPP-4 inhibitors versus SGLT2 inhibitors in medication-naïve individuals with diabetes: A target trial emulation

DOI：https://doi.org/10.1111/dom.70490
2026.01.19

Comprehensive analysis of risk factors for coronavirus disease 2019 infection and post-infection sequelae based on real-world data from a health insurance database in Japan

DOI：https://doi.org/10.1016/j.ijid.2026.108405
2026.01.16

Effects of SGLT2 inhibitors on NSAID-associated acute kidney injury in type 2 diabetes: a claims-based cohort study

DOI：https://doi.org/10.1186/s12882-026-04753-z
2026.01.16

Unfilled Prescriptions in Japan: A 10-Year Retrospective Analysis

DOI：https://doi.org/10.1002/pds.70324
2026.01.15

Hospitalization after Initial Telemedicine Versus in-Person Consultation for Outpatients with Respiratory or Digestive Diseases: A Retrospective Cohort Study

DOI：https://doi.org/10.31662/jmaj.2025-0245
2026.01.10

Epidemiology of herpes zoster and postherpetic neuralgia in Japan: analysis of a large-scale claims database

DOI：https://doi.org/10.1186/s12879-026-12534-0
2026.01.01

Body Roundness Index and Body Shape Index asPredictors for All-Cause Mortality Beyond Body Mass Index:Findings From a National Cohort Study

DOI：https://doi.org/10.1155/jobe/7923338
2025.12.04

Sex differences in the progression of cardiovascular-kidney-metabolic syndrome

DOI：https://doi.org/10.1093/ehjopen/oeaf162
2025.12.02

Linkage of medical administrative claims and long-term care claims in DeSC database

DOI：https://doi.org/10.37737/ace.26012
2025.11.25

Time trends in the prescription of sodium-glucose co-transporter-2 inhibitors based on a claims database in Japan from 2014 to 2022: expanded use in older adults, those with comorbidities, and those potentially initiating diabetes treatment

DOI：https://doi.org/10.1007/s13340-025-00857-3
2025.11.18

Effect of a financial incentive scheme on promoting prescription of biosimilars: a interrupted time-series analyses

DOI：https://doi.org/10.37737/ace.26007
2025.11.10

Visit-to-visit blood pressure variability and dementia risk after considering antihypertensive treatment: real-world data from the Japanese National Health Insurance

DOI：https://doi.org/10.1038/s41440-025-02451-1
2025.11.02

Evolving trends of antidiabetic agents stratified by age, kidney function and body mass index: Insights from a nationwide claims database

DOI： https://doi.org/10.1111/dom.70255
2025.10.25

Cardiovascular Adverse Events Associated with Denosumab Versus Zoledronic Acid in Patients with Breast Cancer: A Propensity Score Overlap Weighted Analysis

DOI：https://doi.org/10.1007/s10549-025-07720-8
2025.10.24

Association of changes in body weight and waist circumference with a subsequent risk of developing hypertension in men requiring specific healthcare guidance

DOI：https://doi.org/10.1038/s41440-025-02397-4
2025.10.23

Economic Impact of Self-Injected Biologics for Rheumatoid Arthritis in Japan: A Propensity Score-Matched Analysis From a Public Healthcare Payer Perspective

DOI：https://doi.org/10.1016/j.vhri.2025.101511
2025.10.11

Treatment Patterns and Healthcare Resource Utilization Among Patients with Obstructive Hypertrophic Cardiomyopathy in Japan: A Claims Database Study

DOI：https://doi.org/10.1007/s40119-025-00431-7
2025.10.01

Work productivity by diseases diagnosed among workers: a study using large-scale claims data and survey data of workers in Japan

DOI：https://doi.org/10.1093/joccuh/uiaf055
2025.09.26

Constipation and Incident Cardiovascular Disease: A Nationwide, Real-World Cohort Study

DOI：https://doi.org/10.1016/j.jacasi.2025.07.027
2025.09.24

Discontinuation of Semaglutide Among Older Adults With Diabetes in the US and Japan

DOI：https://doi.org/10.1001/jamacardio.2025.3109
2025.09.21

Trends in Nonsurgical Interventions and Analgesic Medications for Low Back Pain: A Large Claims Database Study in Japan

DOI：https://doi.org/10.1111/papr.70080
2025.09.19

Associations among nonrestorative sleep status, sleep apnea syndrome, and major adverse cardiac and cerebrovascular events: health check-up and claims data in Japan

DOI：https://doi.org/10.1093/sleep/zsaf290
2025.09.17

Preoperative treatment and postoperative outcomes in osteoporotic patients with vertebral fractures: a longitudinal database study

DOI：https://doi.org/10.1007/s00774-025-01639-2
2025.09.16

Adherence to monitoring iron indices at the initiation of erythropoiesis-stimulating agents or hypoxia-inducible factor prolyl hydroxylase inhibitors

DOI：https://doi.org/10.1007/s10157-025-02761-1
2025.09.04

Effectiveness of treatment initiation for secondary fracture prevention in the older population: Japanese Bone-fracture Osteoporosis in Late-stage population Database study (J-BOLD) – emulation of a randomized target trial

DOI：https://doi.org/10.1007/s00198-025-07687-8
2025.09.01

Polydoctoring and health outcomes among the very old population with multimorbidity: a retrospective cohort study in Japan

DOI：https://doi.org/10.1038/s41598-025-18178-5
2025.08.28

Dietary Habits and Osteoporotic Fracture Risk: Retrospective Cohort Study Using Large-Scale Claims Data

DOI：https://doi.org/10.1210/jendso/bvaf127
2025.08.28

Cardiovascular-kidney-metabolic syndrome stage predicts cardiovascular outcomes in cancer patients: a real-world data analysis of a nationwide epidemiological dataset

DOI：https://doi.org/10.1093/ehjopen/oeaf115
2025.08.18

NSAID-Induced acute kidney injury risk in patients on renin-angiotensin system inhibitors and diuretics: nationwide cohort study

DOI：https://doi.org/10.1186/s40780-025-00485-8
2025.08.18

Novel hypnotics use and hip fracture risk in middle-aged and older adults: A large, population-based cohort study in Japan

DOI：https://doi.org/10.1002/pcn5.70193
2025.08.18

Gender differences in the prescription of SGLT2 inhibitors in chronic kidney disease: A real-world database study

DOI：https://doi.org/10.1111/dom.70020
2025.08.12

Sodium–glucose co-transporter-2 inhibitors versus metformin in reducing osteoarthritis risk: A retrospective cohort study of health insurance claims and check-up data

DOI：https://doi.org/10.1093/jbmrpl/ziaf132
2025.07.30

External Validation of a Risk Prediction Model for Atherosclerotic Cardiovascular Diseases in a Large National Health‐Checkup and Claim Database

DOI：https://doi.org/10.1161/jaha.124.040386
2025.07.30

Association Between Patients’ Admission to the ICU and Psychological Disorders in Their Families: A Retrospective Matched-Pair Cohort Study

DOI：https://doi.org/10.1097/ccm.0000000000006793
2025.07.22

Comprehensive Conservative Kidney Management among Older Population: A Nationwide Administrative Claims Database Analysis

DOI：https://doi.org/10.34067/kid.0000000923
2025.07.17

Real-world status of continuous positive airway pressure (CPAP) persistence in patients with sleep apnea syndrome (SAS): a retrospective longitudinal study of administrative claims data in Japan

DOI：https://doi.org/10.1007/s11325-025-03417-w
2025.07.15

Association between ramelteon use and risk of fragility fractures: A retrospective cohort study

DOI：https://doi.org/10.1007/s11657-025-01582-9
2025.07.11

Osteoarthritis risk associated with romosozumab compared with teriparatide in individuals with osteoporosis: A target trial emulation study

DOI：https://doi.org/10.1016/j.ard.2025.06.2124
2025.07.09

Prevalence, Diagnosis, and Treatment of Generalized Anxiety Disorder in Working Individuals: A Cross-Sectional Study Using Health Claims and Survey Data in Japan

DOI：https://doi.org/10.2147/NDT.S513964
2025.07.02

Association of lean mass index with a risk of incident stroke: a nationwide epidemiological cohort study

DOI：https://doi.org/10.1016/j.jjcc.2025.06.003
2025.06.25

Sex Differences in Electrolyte Disturbances Among Diuretic Users According to Renal Function and Age

DOI：https://doi.org/10.1007/s40264-025-01564-3
2025.06.25

Association between nonrestorative sleep status and sleep apnea syndrome: A cross-sectional and longitudinal study using health check-up and health insurance claims data in Japan

DOI：https://doi.org/10.1016/j.resinv.2025.06.010
2025.06.24

Lean body mass index and the risk of diabetes onset: A nationwide epidemiological cohort study

DOI：https://doi.org/10.1111/jdi.70102
2025.06.22

Impact of 2014 Japanese practice guidelines on treatment patterns in patients with myasthenia gravis: an insurance claims database study

DOI：https://doi.org/10.1136/bmjopen-2024-095496
2025.06.17

Clinical practice and outcome of patients with elderly-onset ulcerative colitis: Insights from a nationwide claims database study in Japan

DOI：https://doi.org/10.1002/jgh3.13103
2025.06.12

Multiple or Single Endocrine Abnormalities Associated with Immune Checkpoint Inhibitors

DOI：https://doi.org/10.1210/clinem/dgaf347
2025.06.11

Association of Migraine Comorbidities with Quality of Life, Work Productivity and Daily Activities: Survey and Medical Claims Data in Japan

DOI：https://doi.org/10.1007/s12325-025-03236-1
2025.06.03

Factors associated with severe lower extremity artery disease in type 2 diabetes based on a large scale claims database in Japan

DOI：https://doi.org/10.1038/s41598-025-03797-9
2025.05.27

The diagnostic status of chronic kidney disease in a real-world database in Japan: CHECK-CKD

DOI：https://doi.org/10.1007/s10157-025-02682-z
2025.05.23

App-Recorded Daily Step Counts, Sex Differences, and Risk of Cardiovascular Outcomes Among Middle-Aged Population

DOI：https://doi.org/10.1161/jaha.124.040402
2025.05.15

Comparative effectiveness of romosozumab versus teriparatide for fracture prevention: A new-user, active comparator design

DOI：https://doi.org/10.1016/j.bone.2025.117523
2025.05.13

Ocular adverse events of perioperative adjuvant docetaxel vs paclitaxel for breast cancer: propensity-score overlap-weighted analysis

DOI：https://doi.org/10.1007/s10549-025-07720-8
2025.05.01

Current Epidemiological and Clinical Features of Sarcoidosis in Japan: A Nationwide Claims Data Study

DOI：https://doi.org/10.7759/cureus.83328
2025.04.28

Difference in Age- and Sex-adjusted Prevalence of Diseases between Employees and Nonemployees with Health Insurance in Japan

DOI：https://doi.org/10.31662/jmaj.2024-0281
2025.04.01

Prescription patterns of comedications associated with drug-drug interactions risk in HCV-infected patients undergoing direct-acting antiviral treatment: an analysis of an administrative claims database in Japan

DOI：https://doi.org/10.1186/s40780-025-00442-5
2025.03.28

Family pharmacist system for patients with chronic cardiovascular or endocrine disease

DOI：https://doi.org/10.1001/jamanetworkopen.2025.60398
2025.03.25

Patient Journey to Transthyretin Cardiac Amyloidosis Diagnosis -A Japanese Claims Database Study –

DOI：https://doi.org/10.1253/circj.CJ-24-0666
2025.03.18

Association between immune checkpoint inhibitors and uveitis in patients with lung cancer, renal cell carcinoma, or malignant melanoma

DOI：https://doi.org/10.1016/j.jcjo.2025.02.010
2025.02.21

Comparison of Efficacies of a Blonanserin Transdermal Patch and Blonanserin Oral Formulation for Psychiatric Symptoms in Patients With Schizophrenia Treated With Laxatives Using a Japanese Claims Database

DOI：https://doi.org/10.1002/npr2.70003
2025.02.15

Quality-adjusted Life Years and Costs of Mechanical Thrombectomy for Very Elderly Patients with Acute Ischaemic Stroke

DOI：https://doi.org/10.2176/jns-nmc.2024-0157
2025.02.11

Risk of Fracture Associated with Pregabalin or Mirogabalin Use: A Case-Case-Time-Control Study Based on Japanese Health Insurance Claims Data

DOI：https://doi.org/10.1007/s40264-025-01516-x
2025.02.01

The relationship between depression and cardiovascular disease in older people: results from a large-scale epidemiological cohort study in Japan

DOI：https://doi.org/10.1007/s41999-024-01128-1
2025.01.29

Comparison of the incidence of proteinuria and changes in eGFR among febuxostat and topiroxostat users

DOI：https://doi.org/10.1007/s10157-025-02630-x
2025.01.24

Adverse events, including fractures, among older patients receiving mirogabalin versus pregabalin: A retrospective cohort study using a large claims database in Japan

DOI：https://doi.org/10.37737/ace.25008
2025.01.20

Changes in Physical Activity Across Cancer Diagnosis and Treatment Based on Smartphone Step Count Data Linked to a Japanese Claims Database: Retrospective Cohort Study

DOI：https://doi.org/10.2196/58093
2025.01.17

Comparative cardiovascular safety of romosozumab versus bisphosphonates in Japanese patients with osteoporosis: a new-user, active comparator design with instrumental variable analyses

DOI：https://doi.org/10.1093/jbmr/zjaf010
2025.01.16

Quality of Life in Adults with Atopic Dermatitis in Relation to Disease Severity: Nationwide Data in Japan

DOI：https://doi.org/10.1007/s13555-024-01333-7
2025.01.15

Prevalence, Patient Characteristics, and Treatment of Patients with Hypertrophic Cardiomyopathy: A Nationwide Payer Database Study

DOI：https://doi.org/10.1007/s40119-024-00396-z
2025.01.10

Sex-specific association of comorbid heart failure on mortality after Alzheimer’s disease diagnosis in older adults aged 75 years and above: A health insurance claims data analysis in Japan

DOI：https://doi.org/10.1177/13872877241305813
2025.01.07

Cardiovascular Safety and Fracture Prevention Effectiveness of Denosumab Versus Oral Bisphosphonates in Patients Receiving Dialysis : A Target Trial Emulation.

DOI：https://doi.org/10.7326/ANNALS-24-03237
2024.12.20

Association of estimated glomerular filtration rate with the incidence of sleep apnea syndrome

DOI：https://doi.org/10.1093/sleep/zsae302
2024.12.20

Real-world treatment patterns and survival in extensive stage small-cell lung cancer in Japan

DOI：https://doi.org/10.1093/jjco/hyae175
2024.12.16

Differential coronary heart disease risk among antihypertensive and lipid-lowering medication users versus non-users: A real-world data analysis

DOI：https://doi.org/10.1016/j.jacl.2024.12.006
2024.12.12

Treatment trends and risks of corticosteroid use in adult primary immune thrombocytopenia: a claims database study in Japan

DOI：https://doi.org/10.1007/s12185-024-03897-8
2024.12.10

Assessing the Risk of Gastrointestinal Perforation Associated with COVID-19: A Self-Controlled Case Series Study

DOI：https://doi.org/10.1093/aje/kwae448
2024.12.07

Associated Factors and Causes of Chronic Disease Medication Oversupply

DOI：https://doi.org/10.1248/bpb.b24-00551
2024.12.03

Assessment of the Utilization of Sodium–Glucose Cotransporter-2 Inhibitors in Patients Without Diabetes

DOI： https://doi.org/10.3390/pharma3040027
2024.11.23

Long-term Effectiveness of Financial Incentives for Not Prescribing Unnecessary Antibiotics to Children with Acute Respiratory and Gastrointestinal Infections: A Japan’s Nationwide Quasi-Experimental Study

DOI：https://doi.org/10.1093/cid/ciae577
2024.11.21

Immune checkpoint inhibitor-related type 1 diabetes incidence, risk, and survival association

DOI：https://doi.org/10.1111/jdi.14362
2024.11.19

Constipation among workers with depression/anxiety: a retrospective study using a claims database and survey data in Japan

DOI：https://doi.org/10.1136/bmjopen-2023-083668
2024.11.12

The Burden of Seasonal Influenza and Its Potential Complications Among Older Japanese Adults: A Real-World Database Study

DOI：https://doi.org/10.1111/irv.70032
2024.11.07

Nationwide Epidemiology and Outpatient Healthcare Resource Use of Children with Respiratory Syncytial Virus from 2005 to 2021

DOI：https://doi.org/10.1093/jpids/piae115
2024.11.01

Impact of an mHealth App (Kencom) on Patients with Untreated Hypertension Initiating Antihypertensive Medications: Real-World Cohort Study.

DOI：https://doi.org/10.2196/52266
2024.10.24

Adding Biomarker Change Information to the Kidney Failure Risk Equation Improves Predictive Ability for Dialysis Dependency in eGFR <30 mL/min/1.73m2

DOI：https://academic.oup.com/ckj/advance-article/doi/10.1093/ckj/sfae321/7840435#google_vignette
2024.10.23

Risk of surgical site infections after tooth extraction in chronic kidney disease: A retrospective real-world study in Japan.

DOI：https://doi.org/10.2215/cjn.0000000599
2024.10.05

Estimating the Prevalence of Chronic Kidney Disease in the Older Population Using Health Screening Data in Japan

DOI：https://doi.org/10.1007/s10157-024-02570-y
2024.09.25

Comparative effectiveness and cardiovascular safety of romosozumab versus teriparatide in patients with osteoporosis: a population-based cohort study

DOI：https://doi.org/10.1007/s00198-024-07255-6
2024.09.19

Current use of angiotensin II receptor blockers and angiotensin-converting enzyme inhibitors for hypertension in patients with chronic kidney disease with proteinuria: a cross-sectional study based on real-world data

DOI：https://doi.org/10.1038/s41440-024-01896-0
2024.09.08

Incidence of new fractures in older patients with osteoporosis receiving biosimilar teriparatide or reference products: A retrospective cohort study

DOI：http://doi.org/10.1111/bcp.16243
2024.09.03

Association of oral hypofunction with aspiration pneumonia, fractures, and mortality in older Japanese adults

DOI：https://doi.org/10.1111/ggi.14973
2024.08.30

Association between self‐reported difficulty in chewing or swallowing and frailty in older adults: A retrospective cohort study

DOI：https://doi.org/10.1007/s11357-024-01325-7
2024.08.05

Effect of COVID-19 Infection on Presenteeism: Cohort Study Using Large Health Insurance-Based Data in Japan

DOI：https://doi.org/10.1097/JOM.0000000000003128
2024.08.03

Do Orally Disintegrating Tablets Facilitate Medical Adherence and Clinical Outcomes in Patients with Post‐stroke Dysphagia?

DOI：https://doi.org/10.1007/s00455-024-10737-8
2024.08.01

Prescribing Cascades of Loop Diuretics and Anti-vertigo Drugs Following Treatment with Gabapentinoids and Benzodiazepines: Prescription Sequence Symmetry Analysis of a Large-Scale Claims Database Including Japanese Older Adults

DOI：https://doi.org/10.1007/s40801-024-00446-x
2024.07.31

Comparison of renal prognosis between dipeptidyl peptidase-4 inhibitor users and non-users

DOI：https://doi.org/10.1111/dom.15800
2024.07.15

Effects of Policy Interventions on Psychotropic Polypharmacy in Japanese Older Adults

DOI：https://doi.org/10.1111/psyg.13165
2024.07.12

Quantification of Oversupply of Chronic Disease Medications among Patients Aged ≥55 Years in Japan

DOI：https://doi.org/10.1248/bpb.b24-00153
2024.07.01

Quality of life and work productivity and activity impairment among online survey respondents with migraine across a range of headache frequency

DOI：https://doi.org/10.3389/fneur.2024.1440733
2024.06.18

Impact of diabetes on mortality and hospitalization after dementia diagnosis: Health insurance claims data analysis

DOI：http://doi.org/10.1111/ggi.14926
2024.06.10

Significance of eGFR and proteinuria for cardiovascular disease in individuals beyond 85 years

DOI：https://doi.org/10.1093/ndt/gfae124
2024.06.05

Usability of the Japanese Late‐Stage Elderly Questionnaire for screening major depression

DOI：http://doi.org/10.1111/psyg.13146
2024.05.29

Preventive dental care reduces risk of cardiovascular disease and pneumonia in hemodialysis population: a nationwide claims database analysis

DOI：https://doi.org/10.1038/s41598-024-62735-3
2024.05.01

Comparative Effectiveness of Long-Acting Injectable Versus Oral Antipsychotics in Patients With Schizophrenia Using the Prevalent New User Design and Subgroup Analyses

DOI：https://doi.org/10.1097/JCP.0000000000001841
2024.05.01

A study to investigate the prevalence of headache disorders and migraine conducted using medical claims data and linked results from online surveys: post-hoc analysis of other headache disorders

DOI：https://doi.org/10.1186/s12883-024-03675-3
2024.04.13

Glycemic control of once-weekly and other administration frequencies for DPP-4 inhibitor in patients with type 2 diabetes: a real-world retrospective cohort study

DOI：https://doi.org/10.1007/s13340-024-00718-5
2024.04.03

Comparison of medication persistence and adherence in type 2 diabetes using a once-weekly regimen of DPP-4 inhibitor compared with once-daily and twice-daily regimens: a retrospective cohort study of Japanese health insurance claims data

DOI：https://doi.org/10.1007/s13340-024-00714-9
2024.04.01

Characteristics of patients who seek medical attention for headache and those who do not: cross-sectional survey and linked medical claims data analysis in Japan

DOI：https://doi.org/10.1136/bmjopen-2023-077686
2024.03.19

Applying the HARMS2-AF Risk Score for Japanese population: An analysis of a nationwide epidemiological dataset

DOI：https://doi.org/10.1093/eurjpc/zwae111
2024.02.17

Association Between Subjective Physical Function and Occurrence of New Fractures in Older Adults: A Retrospective Cohort Study

DOI：https://doi.org/10.1111/ggi.14830
2024.02.13

Impact of COVID-19 Infection on Health-Related Quality of Life in the Japanese Population: A Large Health-Insurance-Based Database Study

DOI：https://doi.org/10.3390/ijerph21020217
2024.02.01

Clinical Utilization of Generic Drugs and Biosimilars for Ulcerative Colitis Treatment: Insights from a Nationwide Database Study in Japan

DOI：https://doi.org/10.1159/000536146
2024.02.01

Association Between Vonoprazan and the Risk of Gastric Cancer After Helicobacter pylori Eradication

DOI：https://doi.org/10.1016/j.cgh.2024.01.037
2024.01.09

Novel subgroups of obesity and their association with outcomes: a data-driven cluster analysis

DOI：https://doi.org/10.1186/s12889-024-17648-1
2023.12.12

Proteinuria screening and risk of bone fracture: a retrospective cohort study using a nationwide population-based database

DOI：https://doi.org/10.1093/ckj/sfad302
2023.11.27

Validation and comparison of the coding algorithms to identify people with migraine using Japanese claims data

DOI：https://doi.org/10.3389/fneur.2023.1231351
2023.10.28

Prevalence, treatment status, medical costs, quality of life, and productivity loss in Japanese adult patients with anemia: a real-world database study

DOI：https://doi.org/10.1080/13696998.2023.2271752
2023.10.23

The impact of clinical inertia on uncontrolled blood pressure in treated hypertension: Real-world, longitudinal data from Japan

DOI：https://doi.org/10.1038/s41440-023-01452-2
2023.09.08

Real-world prevalence, time of diagnosis, and co-occurrence patterns of birth defects in live-born infants, 2014–2020: A health administrative database study in Japan

DOI：https://doi.org/10.1002/bdr2.2247
2023.09.01

Usefulness and difficulties with the thiopurine pharmacogenomic NUDT15 genotyping test: Analysis of real-world data in Japan

DOI：https://doi.org/10.1016/j.jphs.2023.09.002
2023.06.24

Practice patterns and costs of glaucoma treatment in Japan

DOI：https://doi.org/10.1007/s10384-023-01002-w
2023.05.17

Multimorbidity, Polypharmacy, Severe Hypoglycemia, and Glycemic Control in Patients Using Glucose-Lowering Drugs for Type 2 Diabetes: A Retrospective Cohort Study Using Health Insurance Claims in Japan

DOI：doi: 10.1007/s13300-023-01421-5
2023.05.01

The prevalence of end-of-life chemotherapy and targeted therapy in Japan, assessed using a health claims database

DOI：https://doi.org/10.1007/s00280-023-04535-6
2023.02.21

Clinical characteristics, medication use, and impact of primary headache on daily activities: an observational study using linked online survey and medical claims data in Japan

DOI：https://doi.org/10.1186/s12883-023-03122-9
2023.01.25

Association Between Early Surgery and Postoperative Opioid Use in Patients With Lumbar Disc Herniation: A Propensity Score-Matching Analysis Using an Administrative Claims Database in Japan

DOI：https://doi.org/10.1177/21925682231154854
2023.01.25

Comparative effectiveness of long-acting injectable antipsychotics in patients with schizophrenia in Japan

DOI：https://doi.org/10.1016/j.schres.2023.01.019
2022.12.19

Risk of post-extraction bleeding with direct oral anticoagulant compared with warfarin: Retrospective cohort study using large scale claims data in Japan

DOI：https://doi.org/10.1016/j.thromres.2022.12.007
2022.12.12

Recent trends in anti-vascular endothelial growth factor intravitreal injections: A large claims database study in Japan

DOI：https://doi.org/10.1007/s10384-022-00969-2
2022.11.29

Association between COVID-19 pandemic and mental disorders in spouses of intensive care unit patients

DOI：https://doi.org/10.1007/s00134-022-06941-5
2022.11.22

Comparison of bleeding following gastrointestinal endoscopic biopsy in patients treated with and without direct oral anticoagulants

DOI：https://doi.org/10.1055/a-1981-2946
2022.10.06

Postoperative Adverse Events and Re-treatment among Patients who have undergone Laparoscopic and Robotic Sacrocolpopexy for Pelvic Organ Prolapse in Japan

DOI：https://doi.org/10.1002/ijgo.14497
2022.07.15

Association of Smartphone‐Recorded Steps Over Years and Change in Cardiovascular Risk Factors Among Working‐Age Adults

DOI：https://doi.org/10.1161/JAHA.121.025689
2022.06.23

A study to investigate the prevalence of headache disorders and migraine among people registered in a health insurance association in Japan

DOI：https://doi.org/10.1186/s10194-022-01439-3
2022.06.20

Time-series analysis of blood pressure changes after the guideline update in 2019 and the coronavirus disease pandemic in 2020 using Japanese longitudinal data

DOI：https://doi.org/10.1038/s41440-022-00961-w
2022.04.15

Prevalence of Noncommunicable Diseases in Japan Using a Newly Developed Administrative Claims Database Covering Young, Middle-aged, and Elderly People

DOI：https://doi.org/10.31662/jmaj.2021-0189
2021.07.15

The impact of COVID-19 pandemic on the utilization of ambulatory care for patients with chronic neurological diseases in Japan: Evaluation of an administrative claims database

DOI：https://doi.org/10.5582/bst.2021.01194
2021.04.26

Effects of an mHealth App (Kencom) With Integrated Functions for Healthy Lifestyles on Physical Activity Levels and Cardiovascular Risk Biomarkers: Observational Study of 12,602 Users.

DOI：https://doi.org/10.2196/21622